Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50108639 (CHEMBL3596448) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. Curated by ChEMBL | Assay Description Displacement of [125I]-substance P from gerbil NK1 receptor expressed in HEK293 cell membranes incubated for 30 mins by liquid scintillation counting... | Bioorg Med Chem Lett 25: 3039-43 (2015) Article DOI: 10.1016/j.bmcl.2015.04.098 BindingDB Entry DOI: 10.7270/Q24M9690 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50108631 (CHEMBL3596446) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. Curated by ChEMBL | Assay Description Displacement of [125I]-substance P from gerbil NK1 receptor expressed in HEK293 cell membranes incubated for 30 mins by liquid scintillation counting... | Bioorg Med Chem Lett 25: 3039-43 (2015) Article DOI: 10.1016/j.bmcl.2015.04.098 BindingDB Entry DOI: 10.7270/Q24M9690 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50108638 (CHEMBL3596447) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. Curated by ChEMBL | Assay Description Displacement of [125I]-substance P from gerbil NK1 receptor expressed in HEK293 cell membranes incubated for 30 mins by liquid scintillation counting... | Bioorg Med Chem Lett 25: 3039-43 (2015) Article DOI: 10.1016/j.bmcl.2015.04.098 BindingDB Entry DOI: 10.7270/Q24M9690 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50290861 (5-{3-[1-(3,5-Dichloro-phenyl)-ethoxy]-2-phenyl-pip...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.0900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonism of NK1 receptor in rat liver microsomes. | Bioorg Med Chem Lett 7: 2959-2962 (1997) Article DOI: 10.1016/S0960-894X(97)10118-4 BindingDB Entry DOI: 10.7270/Q2W66KRX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50220136 (3-[2-{1-[3,5-di(trifluoromethyl)phenyl]ethoxy}-3-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.0900 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. Curated by ChEMBL | Assay Description Displacement of [125I]-substance P from gerbil NK1 receptor expressed in HEK293 cell membranes incubated for 30 mins by liquid scintillation counting... | Bioorg Med Chem Lett 25: 3039-43 (2015) Article DOI: 10.1016/j.bmcl.2015.04.098 BindingDB Entry DOI: 10.7270/Q24M9690 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50001450 ((SP)Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of Tachykinin receptor 1 of rat forebrain tissue | J Med Chem 35: 1273-9 (1992) BindingDB Entry DOI: 10.7270/Q2222SQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50001450 ((SP)Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity towards Tachykinin receptor 1 in rat cerebral cortex membranes was determined by using 125 [I]-BHSP as radioligand | Bioorg Med Chem Lett 2: 559-564 (1992) Article DOI: 10.1016/S0960-894X(01)81197-5 BindingDB Entry DOI: 10.7270/Q2N01717 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50009228 (CHEMBL413846 | SP (substance P) | Spantide) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligand | J Med Chem 34: 1751-3 (1991) BindingDB Entry DOI: 10.7270/Q2JQ11MP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50001450 ((SP)Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to standard Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50290865 (3-[1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-2-ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonism of NK1 receptor in rat liver microsomes. | Bioorg Med Chem Lett 7: 2959-2962 (1997) Article DOI: 10.1016/S0960-894X(97)10118-4 BindingDB Entry DOI: 10.7270/Q2W66KRX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50290856 (3-[1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-2-ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonism of NK1 receptor in rat liver microsomes. | Bioorg Med Chem Lett 7: 2959-2962 (1997) Article DOI: 10.1016/S0960-894X(97)10118-4 BindingDB Entry DOI: 10.7270/Q2W66KRX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50290859 (5-{3-[1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonism of NK1 receptor in rat liver microsomes. | Bioorg Med Chem Lett 7: 2959-2962 (1997) Article DOI: 10.1016/S0960-894X(97)10118-4 BindingDB Entry DOI: 10.7270/Q2W66KRX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50052280 ((2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 0.180 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonism of NK1 receptor in rat liver microsomes. | Bioorg Med Chem Lett 7: 2959-2962 (1997) Article DOI: 10.1016/S0960-894X(97)10118-4 BindingDB Entry DOI: 10.7270/Q2W66KRX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50106366 (CHEMBL3596493) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. Curated by ChEMBL | Assay Description Displacement of [125I]-substance P from gerbil NK1 receptor expressed in HEK293 cell membranes incubated for 30 mins by liquid scintillation counting... | Bioorg Med Chem Lett 25: 3039-43 (2015) Article DOI: 10.1016/j.bmcl.2015.04.098 BindingDB Entry DOI: 10.7270/Q24M9690 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50106365 (CHEMBL3596492) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. Curated by ChEMBL | Assay Description Displacement of [125I]-substance P from gerbil NK1 receptor expressed in HEK293 cell membranes incubated for 30 mins by liquid scintillation counting... | Bioorg Med Chem Lett 25: 3039-43 (2015) Article DOI: 10.1016/j.bmcl.2015.04.098 BindingDB Entry DOI: 10.7270/Q24M9690 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50106358 (CHEMBL3596485) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. Curated by ChEMBL | Assay Description Displacement of [125I]-substance P from gerbil NK1 receptor expressed in HEK293 cell membranes incubated for 30 mins by liquid scintillation counting... | Bioorg Med Chem Lett 25: 3039-43 (2015) Article DOI: 10.1016/j.bmcl.2015.04.098 BindingDB Entry DOI: 10.7270/Q24M9690 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50001450 ((SP)Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.370 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for inhibition of tachykinin 1 (NK1) receptor in rat brain synaptosomal membranes using [125I]-BH-SP as radioligand | Bioorg Med Chem Lett 3: 447-450 (1993) Article DOI: 10.1016/S0960-894X(01)80229-8 BindingDB Entry DOI: 10.7270/Q2R2119Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50106367 (CHEMBL3596494) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.390 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. Curated by ChEMBL | Assay Description Displacement of [125I]-substance P from gerbil NK1 receptor expressed in HEK293 cell membranes incubated for 30 mins by liquid scintillation counting... | Bioorg Med Chem Lett 25: 3039-43 (2015) Article DOI: 10.1016/j.bmcl.2015.04.098 BindingDB Entry DOI: 10.7270/Q24M9690 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50001450 ((SP)Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.410 | n/a | n/a | n/a | n/a | n/a | n/a |
Mississippi State University Curated by ChEMBL | Assay Description Displacement of [125I]Lys3-substance P from rat NK1 receptor expressed in CHO cells | J Med Chem 50: 6501-6 (2007) Article DOI: 10.1021/jm070577s BindingDB Entry DOI: 10.7270/Q2RX9BT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50106356 (CHEMBL3596483) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.450 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. Curated by ChEMBL | Assay Description Displacement of [125I]-substance P from gerbil NK1 receptor expressed in HEK293 cell membranes incubated for 30 mins by liquid scintillation counting... | Bioorg Med Chem Lett 25: 3039-43 (2015) Article DOI: 10.1016/j.bmcl.2015.04.098 BindingDB Entry DOI: 10.7270/Q24M9690 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50407164 (CHEMBL2115376) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ P. et M. Curie Curated by ChEMBL | Assay Description Concentration required to inhibit the specific binding of [125I]BH-SP to Neurokinin-1 (NK-1) receptor in rat brain synaptosomes | J Med Chem 37: 1586-601 (1994) BindingDB Entry DOI: 10.7270/Q2571CN1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50001450 ((SP)Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.640 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ P. et M. Curie Curated by ChEMBL | Assay Description Concentration required to inhibit the specific binding of [125I]BH-SP to Neurokinin-1 (NK-1) receptor in rat brain synaptosomes | J Med Chem 37: 1586-601 (1994) BindingDB Entry DOI: 10.7270/Q2571CN1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50614481 (CHEMBL5269970) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | UniChem | n/a | n/a | 0.640 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50229589 (Arg-Pro-Lys-Pro-Ala-Gln-Phe-Phe-Gly-Leu-Met-NH2 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.740 | n/a | n/a | n/a | n/a | n/a | n/a |
Mississippi State University Curated by ChEMBL | Assay Description Displacement of [125I]Lys3-substance P from rat NK1 receptor expressed in CHO cells | J Med Chem 50: 6501-6 (2007) Article DOI: 10.1021/jm070577s BindingDB Entry DOI: 10.7270/Q2RX9BT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50049468 ((2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonism of NK1 receptor in rat liver microsomes. | Bioorg Med Chem Lett 7: 2959-2962 (1997) Article DOI: 10.1016/S0960-894X(97)10118-4 BindingDB Entry DOI: 10.7270/Q2W66KRX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50106359 (CHEMBL3596486) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.910 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. Curated by ChEMBL | Assay Description Displacement of [125I]-substance P from gerbil NK1 receptor expressed in HEK293 cell membranes incubated for 30 mins by liquid scintillation counting... | Bioorg Med Chem Lett 25: 3039-43 (2015) Article DOI: 10.1016/j.bmcl.2015.04.098 BindingDB Entry DOI: 10.7270/Q24M9690 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50290863 (3-[1-(3,5-Dichloro-phenyl)-ethoxy]-2-phenyl-piperi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.910 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonism of NK1 receptor in rat liver microsomes. | Bioorg Med Chem Lett 7: 2959-2962 (1997) Article DOI: 10.1016/S0960-894X(97)10118-4 BindingDB Entry DOI: 10.7270/Q2W66KRX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50108630 (CHEMBL3596482) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.930 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. Curated by ChEMBL | Assay Description Displacement of [125I]-substance P from gerbil NK1 receptor expressed in HEK293 cell membranes incubated for 30 mins by liquid scintillation counting... | Bioorg Med Chem Lett 25: 3039-43 (2015) Article DOI: 10.1016/j.bmcl.2015.04.098 BindingDB Entry DOI: 10.7270/Q24M9690 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM21021 (Bifunctional Peptide Ligand, 5 (TY005) | CHEMBL389...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona Curated by ChEMBL | Assay Description Displacement of [3H]substance P from rat NK1 receptor expressed in CHO cell membrane by liquid scintillation counting | J Med Chem 51: 6334-47 (2008) Article DOI: 10.1021/jm800389v BindingDB Entry DOI: 10.7270/Q26T0MF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50106357 (CHEMBL3596484) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. Curated by ChEMBL | Assay Description Displacement of [125I]-substance P from gerbil NK1 receptor expressed in HEK293 cell membranes incubated for 30 mins by liquid scintillation counting... | Bioorg Med Chem Lett 25: 3039-43 (2015) Article DOI: 10.1016/j.bmcl.2015.04.098 BindingDB Entry DOI: 10.7270/Q24M9690 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50106361 (CHEMBL3596488) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. Curated by ChEMBL | Assay Description Displacement of [125I]-substance P from gerbil NK1 receptor expressed in HEK293 cell membranes incubated for 30 mins by liquid scintillation counting... | Bioorg Med Chem Lett 25: 3039-43 (2015) Article DOI: 10.1016/j.bmcl.2015.04.098 BindingDB Entry DOI: 10.7270/Q24M9690 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50001450 ((SP)Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Mossakowski Medical Research Centre Polish Academy of Sciences Curated by ChEMBL | Assay Description Displacement of [Leu-3,4,5-3H(N)]-Substance P from NK1 receptor in rat brain homogenate measured after 60 mins by microbeta scintillation counting an... | ACS Med Chem Lett 8: 73-77 (2017) Article DOI: 10.1021/acsmedchemlett.6b00381 BindingDB Entry DOI: 10.7270/Q2348NCR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50106362 (CHEMBL3596489) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. Curated by ChEMBL | Assay Description Displacement of [125I]-substance P from gerbil NK1 receptor expressed in HEK293 cell membranes incubated for 30 mins by liquid scintillation counting... | Bioorg Med Chem Lett 25: 3039-43 (2015) Article DOI: 10.1016/j.bmcl.2015.04.098 BindingDB Entry DOI: 10.7270/Q24M9690 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50049309 (CHEMBL348976 | N-[(R)-1-{[Acetyl-(2-methoxy-benzyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibitory activity of the compound against Tachykinin receptor 1 in rat brain using [125I]-labeled Boltan-Hunter substance P as radioligand | J Med Chem 39: 736-48 (1996) Article DOI: 10.1021/jm950616c BindingDB Entry DOI: 10.7270/Q20864C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50001450 ((SP)Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Affinity for rat Tachykinin receptor 1 determined in displacement screening by using radioligand 3,4-[3H]-(L-Pro e2) SP. | J Med Chem 42: 4331-42 (1999) BindingDB Entry DOI: 10.7270/Q2SJ1MBK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50108637 (CHEMBL3596456) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. Curated by ChEMBL | Assay Description Displacement of [125I]-substance P from gerbil NK1 receptor expressed in HEK293 cell membranes incubated for 30 mins by liquid scintillation counting... | Bioorg Med Chem Lett 25: 3039-43 (2015) Article DOI: 10.1016/j.bmcl.2015.04.098 BindingDB Entry DOI: 10.7270/Q24M9690 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50106368 (CHEMBL3596495) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. Curated by ChEMBL | Assay Description Displacement of [125I]-substance P from gerbil NK1 receptor expressed in HEK293 cell membranes incubated for 30 mins by liquid scintillation counting... | Bioorg Med Chem Lett 25: 3039-43 (2015) Article DOI: 10.1016/j.bmcl.2015.04.098 BindingDB Entry DOI: 10.7270/Q24M9690 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50106364 (CHEMBL3596491) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. Curated by ChEMBL | Assay Description Displacement of [125I]-substance P from gerbil NK1 receptor expressed in HEK293 cell membranes incubated for 30 mins by liquid scintillation counting... | Bioorg Med Chem Lett 25: 3039-43 (2015) Article DOI: 10.1016/j.bmcl.2015.04.098 BindingDB Entry DOI: 10.7270/Q24M9690 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50106369 (CHEMBL3596496) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. Curated by ChEMBL | Assay Description Displacement of [125I]-substance P from gerbil NK1 receptor expressed in HEK293 cell membranes incubated for 30 mins by liquid scintillation counting... | Bioorg Med Chem Lett 25: 3039-43 (2015) Article DOI: 10.1016/j.bmcl.2015.04.098 BindingDB Entry DOI: 10.7270/Q24M9690 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50284880 (2-[1-Imino-2-(2-methoxy-phenyl)-ethyl]-4,4-dipheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for its binding affinity to NK1 receptor in [3H]-SP binding assay on rat brain membranes. | Bioorg Med Chem Lett 5: 1591-1594 (1995) Article DOI: 10.1016/0960-894X(95)00277-Z BindingDB Entry DOI: 10.7270/Q2X92B74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50106388 (CHEMBL3596476) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. Curated by ChEMBL | Assay Description Displacement of [125I]-substance P from gerbil NK1 receptor expressed in HEK293 cell membranes incubated for 30 mins by liquid scintillation counting... | Bioorg Med Chem Lett 25: 3039-43 (2015) Article DOI: 10.1016/j.bmcl.2015.04.098 BindingDB Entry DOI: 10.7270/Q24M9690 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50449782 (CHEMBL2370874) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for inhibition of tachykinin 1 (NK1) receptor in rat brain synaptosomal membranes using [125I]-BH-SP as radioligand | Bioorg Med Chem Lett 3: 447-450 (1993) Article DOI: 10.1016/S0960-894X(01)80229-8 BindingDB Entry DOI: 10.7270/Q2R2119Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50030166 (Arg-Pro-Lys-Pro-Gln-Gln-Phe-Pen(S-Me)-Gly-Leu-Met ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ P. et M. Curie Curated by ChEMBL | Assay Description Concentration required to inhibit the specific binding of [125I]BH-SP to Neurokinin-1 (NK-1) receptor in rat brain synaptosomes | J Med Chem 37: 1586-601 (1994) BindingDB Entry DOI: 10.7270/Q2571CN1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50030158 (Arg-Pro-Lys-Pro-Gln-Gln-Phe-Flg-Gly-Leu-Met | CHEM...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ P. et M. Curie Curated by ChEMBL | Assay Description Concentration required to inhibit the specific binding of [125I]BH-SP to Neurokinin-1 (NK-1) receptor in rat brain synaptosomes | J Med Chem 37: 1586-601 (1994) BindingDB Entry DOI: 10.7270/Q2571CN1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50030146 (Arg-Pro-Lys-Pro-Gln-Gln-Phe-Tle-Gly-Leu-Met | CHEM...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ P. et M. Curie Curated by ChEMBL | Assay Description Concentration required to inhibit the specific binding of [125I]BH-SP to Neurokinin-1 (NK-1) receptor in rat brain synaptosomes | J Med Chem 37: 1586-601 (1994) BindingDB Entry DOI: 10.7270/Q2571CN1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50106386 (CHEMBL3596474) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. Curated by ChEMBL | Assay Description Displacement of [125I]-substance P from gerbil NK1 receptor expressed in HEK293 cell membranes incubated for 30 mins by liquid scintillation counting... | Bioorg Med Chem Lett 25: 3039-43 (2015) Article DOI: 10.1016/j.bmcl.2015.04.098 BindingDB Entry DOI: 10.7270/Q24M9690 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50030161 (Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Pro-Leu-Met | CHEM...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ P. et M. Curie Curated by ChEMBL | Assay Description Concentration required to inhibit the specific binding of [125I]BH-SP to Neurokinin-1 (NK-1) receptor in rat brain synaptosomes | J Med Chem 37: 1586-601 (1994) BindingDB Entry DOI: 10.7270/Q2571CN1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50614484 (CHEMBL5268460) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | UniChem | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50614485 (CHEMBL5282996) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | UniChem | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50407162 (CHEMBL2115375) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ P. et M. Curie Curated by ChEMBL | Assay Description Concentration required to inhibit the specific binding of [125I]BH-SP to Neurokinin-1 (NK-1) receptor in rat brain synaptosomes | J Med Chem 37: 1586-601 (1994) BindingDB Entry DOI: 10.7270/Q2571CN1 | |||||||||||
More data for this Ligand-Target Pair |
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